According to a new report published by Introspective Market Research, titled, Plasma Expander Market by Product Type, Application, and End-User, The Global Plasma Expander Market Size Was Valued at USD 6.97 Billion in 2023 and is Projected to Reach USD 20.44 Billion by 2032, Growing at a CAGR of 12.7% from 2024 to 2032. The Global Plasma Expander Market is witnessing substantial growth due to the rising prevalence of blood loss, shock, and trauma-related conditions. Plasma expanders are intravenous solutions that increase the volume of plasma in patients, aiding in maintaining blood pressure and improving tissue perfusion. These solutions are commonly used in hospitals, emergency care, and surgical procedures to stabilize patients before definitive treatment.
Unlike conventional fluid replacement therapies, plasma expanders offer advantages such as rapid volume restoration, reduced risk of fluid overload, and improved circulation efficiency. The market benefits from innovations in synthetic and natural plasma expanders, including hydroxyethyl starch, gelatin-based solutions, and albumin preparations, which enhance patient safety and therapeutic outcomes.
The growing incidence of surgeries, trauma cases, and chronic conditions worldwide, coupled with expanding healthcare infrastructure, particularly in North America and Europe, is driving demand for plasma expanders. Additionally, increasing investment in emergency care and critical care facilities in emerging markets is creating new growth opportunities.
The Plasma Expander Market is segmented into Product Type, Application, and End-User. By Product Type, the market is categorized into (Natural Plasma Expanders, Synthetic Plasma Expanders, and Semi-Synthetic Plasma Expanders). By Application, the market is categorized into (Surgery, Trauma, Shock, Burns, and Others). By End-User, the market is categorized into (Hospitals, Ambulatory Care Centers, and Clinics).
A key growth driver for the Plasma Expander Market is the increasing number of surgical procedures and trauma cases globally. Rising road accidents, injuries, and emergency hospitalizations are driving the urgent need for effective plasma volume replacement solutions. Hospitals and emergency care facilities are increasingly adopting plasma expanders to stabilize patients experiencing acute blood loss. Moreover, advancements in synthetic plasma expanders with improved safety profiles have boosted clinical adoption, ensuring rapid recovery and reducing complications related to hypovolemia, making them an essential component of modern critical care management.
The market presents a significant opportunity in emerging economies, where the development of healthcare infrastructure and increasing access to emergency and critical care facilities are creating a growing demand for plasma expanders. Rising government initiatives to enhance trauma care, combined with an increasing number of surgical interventions, provide pharmaceutical companies and suppliers with potential growth avenues. Additionally, ongoing research into advanced plasma expander formulations with better safety, efficacy, and storage properties offers opportunities for product innovation and expansion into new hospital and clinical segments globally.
Plasma Expander Market, Segmentation
The Plasma Expander Market is segmented on the basis of Product Type, Application, and End-User.
Product Type
The Product Type segment is further classified into Natural Plasma Expanders, Synthetic Plasma Expanders, and Semi-Synthetic Plasma Expanders. Among these, the Synthetic Plasma Expanders sub-segment accounted for the highest market share in 2023. Synthetic solutions, such as hydroxyethyl starch and dextran-based products, are preferred due to their stability, rapid volume expansion, and ease of storage. Hospitals widely use these solutions in critical care and emergency scenarios for trauma and surgery patients, making them the leading segment in the market.
Application
The Application segment is further classified into Surgery, Trauma, Shock, Burns, and Others. Among these, the Surgery sub-segment accounted for the highest market share in 2023. Plasma expanders are crucial during major surgical procedures to maintain hemodynamic stability and prevent hypovolemic shock. Increasing elective and emergency surgeries worldwide have driven the consumption of plasma expanders, with hospitals favoring products that ensure patient safety, rapid recovery, and minimal side effects during perioperative care.
Some of The Leading/Active Market Players Are-
- Baxter International Inc. (USA)
- Grifols, S.A. (Spain)
- Octapharma AG (Switzerland)
- B. Braun Melsungen AG (Germany)
- Terumo Corporation (Japan)
- Haemonetics Corporation (USA)
- CSL Behring AG (Australia)
- Sanquin Plasma Products (Netherlands)
- Kedrion S.p.A (Italy)
- Shandong Taibang Biological Products Co., Ltd. (China)
- and other active players.
Key Industry Developments
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In February 2024, Baxter International expanded its plasma expander production facility in the U.S. to meet increasing global demand.
The expansion involved new state-of-the-art manufacturing lines, enhancing production efficiency and compliance with regulatory standards. This investment supports the growing demand from hospitals and emergency care units, positioning Baxter to cater to critical care requirements worldwide. - In August 2023, Grifols launched a next-generation albumin-based plasma expander designed for rapid volume restoration.
The new product provides improved safety and faster stabilization for trauma and surgery patients. It integrates advanced formulation technologies to reduce potential side effects, ensuring higher clinical adoption in hospital settings globally and strengthening Grifols’ market leadership in plasma expanders.
Key Findings of the Study
- Synthetic plasma expanders dominate product type due to stability and rapid volume expansion.
- Surgical applications account for the largest share owing to high procedural demand.
- North America and Europe lead the market due to advanced healthcare infrastructure.
- Rising trauma cases and emergency care requirements are key growth drivers.
- Emerging markets provide opportunities for expansion with growing hospital infrastructure.
