According to a new report published by Introspective Market Research, titled, “Knee Replacement Prosthesis Market by Product Type, Fixation Type, and End User,” The Global Knee Replacement Prosthesis Market Size Was Valued at USD 12.09 Billion in 2024 and is Projected to Reach USD 19.01 Billion by 2035, Growing at a CAGR of 4.2%.
The knee replacement prosthesis market comprises the design, manufacturing, and distribution of artificial knee implants used in total and partial knee arthroplasty procedures. These sophisticated medical devices replace damaged knee joints caused by osteoarthritis, rheumatoid arthritis, or traumatic injury. Modern prostheses offer significant advantages over earlier generations, including improved materials (like highly cross-linked polyethylene and advanced ceramics), enhanced biomechanics that mimic natural knee kinematics, and greater durability. Innovations such as gender-specific designs, patient-specific instrumentation, and robotic-assisted surgery have further improved surgical precision and patient outcomes.
The primary growth driver for the knee replacement prosthesis market is the demographic surge of an aging global population, particularly the expansion of the over-65 age cohort who are most susceptible to osteoarthritis and degenerative joint diseases. As life expectancy increases, so does the prevalence of age-related conditions that necessitate surgical intervention to maintain mobility and quality of life. Furthermore, the rising incidence of obesity places additional stress on weight-bearing joints, accelerating the need for knee replacements in younger patient demographics. This sustained epidemiological demand, combined with higher patient expectations for active lifestyles post-retirement, creates a robust and expanding patient pool for knee arthroplasty procedures worldwide.
A significant market opportunity lies in the accelerated adoption and integration of enabling technologies such as robotic-assisted surgery, 3D printing for custom implants, and digital patient-specific planning. Robotic systems offer surgeons enhanced precision for implant placement, which is linked to improved long-term outcomes and patient satisfaction. The opportunity for manufacturers is to develop proprietary implant systems designed to work seamlessly with these robotic platforms, creating locked-in ecosystems. Furthermore, the use of 3D printing allows for the production of highly porous, biocompatible implants that promote better osseointegration, particularly in complex revision cases, opening a high-value segment focused on personalized solutions.
Knee Replacement Prosthesis Market, Segmentation
The Knee Replacement Prosthesis Market is segmented on the basis of Product Type, Fixation Type, and End User.
Product Type
The Product Type segment is further classified into Total Knee Replacement, Partial Knee Replacement, and Revision Knee Replacement. Among these, the Total Knee Replacement sub-segment accounted for the highest market share in 2024. This dominance is due to TKR being the standard-of-care procedure for advanced, end-stage osteoarthritis affecting multiple compartments of the knee. It offers comprehensive pain relief and functional restoration for a wide patient demographic. Continuous material and design innovations aimed at improving longevity and range of motion, coupled with its high procedural volume, solidify TKR as the revenue mainstay for implant manufacturers globally.
Fixation Type
The Fixation Type segment is further classified into Cemented, Cementless, and Hybrid. Among these, the Cemented sub-segment accounted for the highest market share in 2024. Cemented fixation remains the gold standard and most widely used technique due to its proven long-term success, reliable immediate stability, and relative technical simplicity. It is suitable for the vast majority of patients, particularly the elderly and those with poorer bone quality. The extensive clinical history, surgeon familiarity, and lower cost compared to cementless options ensure cemented prostheses continue to be the preferred choice in a majority of primary knee replacement surgeries.
Some of The Leading/Active Market Players Are-
- Zimmer Biomet Holdings, Inc. (USA)
- Stryker Corporation (USA)
- Johnson & Johnson (DePuy Synthes) (USA)
- Smith & Nephew plc (UK)
- B. Braun Melsungen AG (Germany)
- Exactech, Inc. (USA)
- Corin Group (UK)
- MicroPort Scientific Corporation (China)
- DJO Global, Inc. (USA)
- Waldemar Link GmbH & Co. KG (Germany)
- Baumer S.A. (Brazil)
- Medacta International (Switzerland)
- ConforMIS, Inc. (USA)
- Össur (Iceland)
- Japan Medical Dynamic Marketing, Inc. (Japan)
- and other active players.
Key Industry Developments
In March 2024, Stryker Corporation received FDA clearance for its latest robotic-arm assisted surgery system update, featuring enhanced software algorithms for total knee arthroplasty planning, further integrating its Mako system with its Triathlon implant portfolio.
This development underscores the strategic push by major players to deepen the synergy between their implant hardware and proprietary robotic software platforms, creating differentiated, technology-driven surgical ecosystems that drive brand loyalty and implant sales.
In January 2024, Zimmer Biomet announced a strategic partnership with a leading health tech firm to develop a remote patient monitoring and digital care pathway platform specifically for patients undergoing knee replacement surgery.
This move highlights the industry's expansion beyond the implant itself into the broader value-based care continuum, using digital tools to improve pre-op preparation, post-op recovery, and long-term outcomes, thereby enhancing patient satisfaction and supporting bundled payment models.
Key Findings of the Study
- Total Knee Replacement implants dominate the product landscape.
- Cemented fixation is the most prevalent method due to its proven reliability.
- Market growth is primarily driven by the aging global population and rising obesity rates.
- North America is the leading regional market, followed by Europe.
- Integration with robotic surgery and digital health platforms is the key technological trend shaping competition.
