“According to a new report published by Introspective Market Research, titled, Intraoperative Radiation Therapy Market by Product Type, Application, and End User, The Global Intraoperative Radiation Therapy Market Size Was Valued at USD 133.07 Million in 2024, and is Projected to Reach USD 292.92 Million by 2035, Growing at a CAGR of 8.21% from 2025–2035.”
The Intraoperative Radiation Therapy (IORT) market is witnessing steady growth driven by the rising prevalence of cancer and the increasing adoption of advanced, precision-based treatment approaches. IORT is a specialized radiation therapy technique that delivers a concentrated dose of radiation directly to a tumor site during surgery, minimizing exposure to surrounding healthy tissues. This targeted approach offers significant advantages over conventional external beam radiation therapy, including reduced treatment time, improved local tumor control, and lower risk of radiation-related complications.
IORT systems are widely used in the treatment of breast cancer, colorectal cancer, brain tumors, and other solid malignancies. The technology is increasingly being integrated into multidisciplinary cancer care due to its ability to enhance surgical outcomes and improve patient quality of life. Growing awareness among clinicians, advancements in mobile and compact radiation delivery systems, and supportive clinical evidence are further strengthening the adoption of intraoperative radiation therapy across hospitals and cancer treatment centers globally.
Market Segmentation
The Intraoperative Radiation Therapy Market is segmented into Product Type, Application, and End User.
- By Product Type, the market is categorized into Electron Beam IORT Systems, X-ray Based IORT Systems, and Accessories.
- By Application, the market is categorized into Breast Cancer, Colorectal Cancer, Brain Tumors, Gynecological Cancers, and Others.
- By End User, the market is categorized into Hospitals, Cancer Research Institutes, and Specialty Clinics.
Growth Driver
One of the primary growth drivers of the Intraoperative Radiation Therapy market is the increasing global burden of cancer and the growing demand for precise and efficient treatment modalities. As healthcare systems focus on improving treatment outcomes while reducing overall therapy duration, IORT has emerged as a highly effective option. The ability to deliver a single, high-dose radiation treatment during surgery reduces the need for multiple post-operative radiation sessions, lowering healthcare costs and improving patient compliance. Additionally, continuous technological advancements in radiation delivery systems are making IORT more accessible and safer, further driving market growth.
Market Opportunity
The market presents significant growth opportunities in emerging economies due to improving healthcare infrastructure and rising investments in oncology care. Increasing awareness of advanced cancer treatment options, coupled with government initiatives to strengthen cancer care facilities, is expected to create new demand for IORT systems. Moreover, ongoing clinical research exploring the use of IORT in additional cancer indications is likely to expand its application scope. Strategic collaborations between medical device manufacturers and healthcare providers to introduce cost-effective and portable IORT solutions also represent a key opportunity for market expansion.
Detailed Segmentation
Intraoperative Radiation Therapy Market, Segmentation
The Intraoperative Radiation Therapy Market is segmented on the basis of Product Type, Application, and End User.
Product Type
The Product Type segment is further classified into Electron Beam IORT Systems, X-ray Based IORT Systems, and Accessories. Among these, the X-ray Based IORT Systems sub-segment accounted for the highest market share in 2024. X-ray based systems are widely preferred due to their compact design, ease of integration into operating rooms, and suitability for a broad range of surgical procedures. These systems enable precise dose delivery with minimal shielding requirements, making them increasingly attractive for hospitals and specialty clinics.
Application
The Application segment is further classified into Breast Cancer, Colorectal Cancer, Brain Tumors, Gynecological Cancers, and Others. Among these, the Breast Cancer sub-segment accounted for the highest market share in 2024. The high adoption of IORT in breast cancer treatment is attributed to strong clinical evidence supporting its effectiveness in early-stage cases, reduced treatment duration, and improved cosmetic outcomes. The growing incidence of breast cancer globally continues to drive demand for IORT in this application area.
Some of The Leading/Active Market Players Are-
• ZEISS Group (Germany)
• Elekta AB (Sweden)
• Sensus Healthcare, Inc. (United States)
• iCAD, Inc. (United States)
• IntraOp Medical Corporation (United States)
• Eckert & Ziegler BEBIG (Germany)
• Varian Medical Systems (United States)
• Panacea Medical Technologies (India)
• Isoray Medical (United States)
• Hitachi, Ltd. (Japan)
• Toshiba Energy Systems & Solutions (Japan)
• Shenzhen Mindray Bio-Medical Electronics Co., Ltd. (China)
and other active players.
Key Industry Developments
In March 2024, a leading medical device manufacturer announced the launch of an advanced mobile IORT system designed for use in standard operating rooms. The system focuses on improved dose accuracy and enhanced safety features.The newly launched system aims to increase the adoption of intraoperative radiation therapy by reducing installation complexity and operational costs. It is expected to support broader clinical use across hospitals with limited radiation infrastructure.
In September 2024, a major hospital network expanded its oncology services by integrating intraoperative radiation therapy into its surgical oncology programs.This expansion reflects the growing clinical confidence in IORT as an effective treatment approach and highlights increasing investments by healthcare providers to offer advanced cancer care solutions.
Key Findings of the Study
• X-ray based IORT systems dominated the product type segment
• Breast cancer remained the leading application segment
• North America accounted for the largest regional share
• Rising cancer prevalence is a key growth driver
• Technological advancements are shaping market trends


