According to a new report published by Introspective Market Research, titled, “Vertebroplasty And Kyphoplasty Market by Product, Procedure, and End-User,” The Global Vertebroplasty And Kyphoplasty Market Size Was Valued at USD 1.68 Billion in 2024 and is Projected to Reach USD 6.57 Billion by 2035, Growing at a CAGR of 13.2% From 2025–2035.
The Vertebroplasty and Kyphoplasty market encompasses minimally invasive surgical procedures and associated devices used to treat painful vertebral compression fractures (VCFs), most commonly caused by osteoporosis, trauma, or cancer metastasis. The procedures involve the percutaneous injection of bone cement (polymethylmethacrylate, PMMA) into the fractured vertebra. Kyphoplasty includes an additional step of inflating a balloon tamp inside the vertebra to create a cavity and restore lost height before cement injection. The core advantage of these procedures over traditional conservative management (bed rest, bracing, pain medication) or open spinal fusion surgery is their ability to rapidly stabilize the fracture, alleviate severe pain, and often restore vertebral height with minimal tissue disruption, leading to faster patient recovery and mobility.
The primary growth driver for the vertebroplasty and kyphoplasty market is the demographic explosion of the global aging population and the consequent rise in the prevalence of osteoporosis and related fragility fractures. As life expectancy increases, a larger segment of the population, particularly postmenopausal women, is living with osteoporosis—a silent disease that dramatically increases the risk of spinal fractures. Each year, millions of osteoporotic vertebral compression fractures occur worldwide, causing debilitating pain, disability, and significant healthcare costs. This creates a vast and growing addressable patient population for whom minimally invasive spine interventions like kyphoplasty offer a highly effective treatment, driving sustained demand for the procedures and the specialized devices that enable them.
A significant market opportunity lies in the development and adoption of advanced biomaterials and next-generation procedural technologies. There is strong clinical demand moving beyond traditional PMMA cement toward osteoconductive, bioactive, and resorbable cements that integrate with natural bone and eliminate concerns about cement leakage or long-term biocompatibility. Concurrently, innovation in instrumentation is focusing on ultra-precise, navigated, and robotic-assisted delivery systems that enhance procedural accuracy and safety. Furthermore, the expansion of indications to include more complex fractures and the younger traumatic injury population presents a substantial growth avenue. Companies leading in these material science and technological innovations are positioned to capture premium market segments and drive the next wave of growth in spinal fracture care.
Vertebroplasty And Kyphoplasty Market, Segmentation
The Vertebroplasty And Kyphoplasty Market is segmented on the basis of Product, Procedure, and End-User.
Procedure
The Procedure segment is further classified into Vertebroplasty and Kyphoplasty. Among these, the Kyphoplasty sub-segment accounted for the highest market share in 2024 and is projected to be the faster-growing segment. Kyphoplasty's dominance is attributed to its significant clinical advantages: the use of a balloon to create a low-pressure cavity for cement allows for more controlled injection, significantly reducing the risk of cement leakage a key complication. Additionally, the balloon can help restore vertebral body height and correct spinal kyphotic deformity, offering not just pain relief but also potential structural improvement. These benefits make it the preferred and often reimbursed option for many surgeons and patients.
End-User
The End-User segment is further classified into Hospitals, Ambulatory Surgical Centers (ASCs), and Specialty Clinics. Among these, the Hospitals sub-segment accounted for the highest market share in 2024. Hospitals remain the dominant setting for these procedures because they have the necessary infrastructure, including advanced imaging (fluoroscopy, CT), emergency departments for acute fracture presentations, and multidisciplinary teams involving spine surgeons, interventional radiologists, and anesthesiologists. They handle the most complex cases, including patients with multiple comorbidities and pathological fractures from cancer, ensuring hospitals are the primary and most critical site for vertebroplasty and kyphoplasty interventions.
Some of The Leading/Active Market Players Are-
• Medtronic plc (Ireland)
• Johnson & Johnson (DePuy Synthes) (US)
• Stryker Corporation (US)
• Globus Medical, Inc. (US)
• Merit Medical Systems, Inc. (US)
• Alphatec Holdings, Inc. (US)
• CareFusion Corporation (BD) (US)
• Zimmer Biomet Holdings, Inc. (US)
• Orthofix Medical Inc. (US)
• G-21 S.r.l. (Italy)
• IZI Medical Products (US)
• and other active players.
Key Industry Developments
In March 2024, Stryker launched its next-generation FAST-FILL Kyphoplasty System featuring a novel high-viscosity cement designed to set more rapidly. This system aims to further reduce cement extravasation risks and shorten procedure time, enhancing safety and efficiency in the treatment of vertebral compression fractures.
In January 2024, Medtronic received CE Mark approval in Europe for its OsteoCool RF Ablation System used in conjunction with vertebroplasty for the treatment of painful spinal metastases. This combination therapy allows for targeted tumor ablation followed by immediate stabilization, offering a minimally invasive option for cancer patients with pathological spinal fractures.
Key Findings of the Study
• The Kyphoplasty procedure and Hospital end-user segment dominate the market.
• North America is the largest regional market due to high procedure adoption and favorable reimbursement.
• The aging global population and rising osteoporosis rates are the key growth drivers.
• Key trends include innovation in bioactive cements and the expansion of indications into oncology.
