Single-Use Bioreactor Market Synopsis

Single-Use Bioreactor Market Size is Valued at USD 4.53 Billion in 2023, and is Projected to Reach USD 16.12 Billion by 2032, Growing at a CAGR of 17.19% From 2024-2032.

The Single-Use Bioreactor (SUB) market refers to the use of bioreactors made of disposables – mostly plastic – used in cell or microorganism culture for the manufacture of biologics, vaccines, or biosimilar products. Biopharmaceutical manufacturing processes are equally using these Bioreactors due to limited contamination risks, high flexibility and low cleaning and sterilization requirements. Such a strategy has made them common in different phases including research and process development, pilot scale and lastly, large scale bioproduction, making it affordable to the manufacturers.

• The Single-Use Bioreactor market is expected to grow mainly due to the growing adoption of biologics vaccines and biosimilars required for the management of lifestyle diseases such as cancer, diabetes mellitus, and autoimmune diseases. That is why SUBs can help the biopharmaceutical firm to increase production capacities and guarantee a high level of quality at the same time. This technology has become popular because it entails fast technological strategies, and it also entails reducing technological operational costs, hence it becomes famous in both biopharmaceutical organizations and enterprises, thus aspiring to be in great demand in the coming years.
• Another important factor is the trend toward increasing sterility and limiting multiple uses of the equipment due to the SUB’s construction for single-use. This feature improves the general safety anddue to its implementation it complies with very high and strict regulatory standards. Also, the rising R&D spending and the incline in collaboration between CROs and biopharmaceutical companies which in turn creates a higher need for single-use bioreactors.

Single-Use Bioreactor Market Trend Analysis

Increasing Applications in the Automotive Industry

• One trend that is currently experienced in the Single-Use Bioreactor market is the continuous enhancement of the technology concerning the scale-up and the production processes. SUBs with larger capacity are being developed to help biopharmaceutical companies transition from laboratory scale to industrial scale with no sacrifice of their product quality. However, advances in automation and sensor technologies incorporated into SUBs offer a capacity to monitor and manage the process in real time, increase the dependability of processes and minimize the possibility of human mistake.
• Another new trend that can be monitored in the SUB market is the issue of Sustainability. In an attempt to reduce on the negative effects of the business on the environment, manufacturers are now shifting their effort in designing disposable materials that meet the environmental standards besides enhancing the recycling of the single use parts of such products. Another trend that biopharmaceutical companies are also implementing is measures of how best to use SUBs while minimizing wastage in their use as well as adherence to the regulations.

The demand for biologics and biosimilars is rising due to the increasing prevalence of chronic diseases

• The Single-Use Bioreactor market has great potential in the emerging economies where the need for the biologics and biosimilars is growing due to the increase of the chronic diseases incidence and developing healthcare system. Asian Pacific, Latin American and Middle East countries are experiencing an addition to the increased investment in biopharmaceutical production facilities, hence are the potential markets for SUB in the future. The SUB technology allows biopharmaceutical companies to establish portable and efficient production systems almost immediately in these markets.
• Another opportunity is in the growing number of personalized medicines that shall call for adaptable bio production methods. Disposable bioreactors give access to the required scalability as well as the flexibility inherent in the mini-scale production that is critical for personalized medicine. This trend affords SUB manufacturers the opportunity to design and construct new, unique bioreactor models that address the burgeoning small markets bearing differentiated treatment.

Single-Use Bioreactor Market Segment Analysis:

Single-Use Bioreactor Market Segmented on the basis of Product type, Cell Type, application, and end-users.

By Product Type, Media bags segment is expected to dominate the market during the forecast period

• The Single-Use Bioreactor market is also segmented by products where: single-use bioreactor systems, media bags, and filtration assemblies. Standalone bioreactor systems are often fully integrated systems for cell culture and bioprocessing and include the primary bioreactor vessel plus associated apparatus for production. Media bags are one of the critical equipment that are used in the packing and transport of cell culture media and buffer solutions for convenience and aseptic reasons during production. Filtration assemblies have highest importance in Bioproducts manufacturing process used to purify and protect bioproducts by removing impurities and particles, thereby enhancing the productivity of the manufacturing process cycle.

By Application, Process development segment held the largest share in 2024

• Single-Use Bioreactors (S.U.Bs.) can be classified, by their applications, for research and development (R&D), process development, and bioproduction. For small-scale R&D usage, including trying out new cell lines, and the initial investigation in the formulation and characteristics of media in the early stages of a biologic’s development, single-use bioreactors offer significant applicability. These bioreactors are applied in process development to standardize conditions for scaling up the production processes, and guarantee a similar efficiency from the end-to-end production processes of lab scale to industrial scale. Bioproduction refers to the commercial-scale production of biologics, and single use bioreactors have become a unique solution for flexibility in production, for cost, and time compared to the stainless-steel systems.

Single-Use Bioreactor Market Regional Insights:

North America is Expected to Dominate the Market Over the Forecast period

• As of now, the Single-Use Bioreactor market is mainly led by North America due to continuous development in the biopharmaceutical sector and rapidly increasing demand for biologics & biosimilars. SUBs are used across the region because of well-developed R& D infrastructure plus high government support and investment in biomanu- facturing. The industry pioneers include the United States where a large number of biopharmaceutical firms employ single-use solutions to enhance the speed of drug discovery and manufacturing.
• Additionally, the North American regulatory authorities including FDA maintain high requirements for production of drugs and this has in equally enhanced the market for SUBs since they conform to these requirements. This is due to the fact that the region’s health care infrastructure is well developed and the incidences of chronic diseases are high therefore constantly in need of biologics hence the call for more efficient biomanufacturing technologies such as single-use bioreactors.

Active Key Players in the Single-Use Bioreactor Market

• Thermo Fisher Scientific (United States)
• Sartorius AG (Germany)
• Danaher Corporation (United States)
• Merck KGaA (Germany)
• GE Healthcare (United States)
• Eppendorf AG (Germany)
• CESCO Bioengineering Co., Ltd. (Taiwan)
• PBS Biotech, Inc. (United States)
• Distek, Inc. (United States)
• Solida Biotech GmbH (Germany)
• Others

Chapter 1: Introduction
 1.1 Scope and Coverage

Chapter 2:Executive Summary

Chapter 3: Market Landscape
 3.1 Market Dynamics
  3.1.1 Drivers
  3.1.2 Restraints
  3.1.3 Opportunities
  3.1.4 Challenges
 3.2 Market Trend Analysis
 3.3 PESTLE Analysis
 3.4 Porter's Five Forces Analysis
 3.5 Industry Value Chain Analysis
 3.6 Ecosystem
 3.7 Regulatory Landscape
 3.8 Price Trend Analysis
 3.9 Patent Analysis
 3.10 Technology Evolution
 3.11 Investment Pockets
 3.12 Import-Export Analysis

Chapter 4: Single-Use Bioreactor Market by Product Type
 4.1 Single-Use Bioreactor Market Snapshot and Growth Engine
 4.2 Single-Use Bioreactor Market Overview
 4.3 Single-use bioreactor systems
  4.3.1 Introduction and Market Overview
  4.3.2 Historic and Forecasted Market Size in Value USD and Volume Units (2017-2032F)
  4.3.3 Key Market Trends, Growth Factors and Opportunities
  4.3.4 Single-use bioreactor systems: Geographic Segmentation Analysis
 4.4 Media bags
  4.4.1 Introduction and Market Overview
  4.4.2 Historic and Forecasted Market Size in Value USD and Volume Units (2017-2032F)
  4.4.3 Key Market Trends, Growth Factors and Opportunities
  4.4.4 Media bags: Geographic Segmentation Analysis
 4.5 Filtration assemblies
  4.5.1 Introduction and Market Overview
  4.5.2 Historic and Forecasted Market Size in Value USD and Volume Units (2017-2032F)
  4.5.3 Key Market Trends, Growth Factors and Opportunities
  4.5.4 Filtration assemblies: Geographic Segmentation Analysis

Chapter 5: Single-Use Bioreactor Market by Cell Type
 5.1 Single-Use Bioreactor Market Snapshot and Growth Engine
 5.2 Single-Use Bioreactor Market Overview
 5.3 Mammalian cells
  5.3.1 Introduction and Market Overview
  5.3.2 Historic and Forecasted Market Size in Value USD and Volume Units (2017-2032F)
  5.3.3 Key Market Trends, Growth Factors and Opportunities
  5.3.4 Mammalian cells: Geographic Segmentation Analysis
 5.4 Bacterial cells
  5.4.1 Introduction and Market Overview
  5.4.2 Historic and Forecasted Market Size in Value USD and Volume Units (2017-2032F)
  5.4.3 Key Market Trends, Growth Factors and Opportunities
  5.4.4 Bacterial cells: Geographic Segmentation Analysis
 5.5 Yeast cells
  5.5.1 Introduction and Market Overview
  5.5.2 Historic and Forecasted Market Size in Value USD and Volume Units (2017-2032F)
  5.5.3 Key Market Trends, Growth Factors and Opportunities
  5.5.4 Yeast cells: Geographic Segmentation Analysis
 5.6
  5.6.1 Introduction and Market Overview
  5.6.2 Historic and Forecasted Market Size in Value USD and Volume Units (2017-2032F)
  5.6.3 Key Market Trends, Growth Factors and Opportunities
  5.6.4 : Geographic Segmentation Analysis

Chapter 6: Single-Use Bioreactor Market by Application
 6.1 Single-Use Bioreactor Market Snapshot and Growth Engine
 6.2 Single-Use Bioreactor Market Overview
 6.3 Research and development
  6.3.1 Introduction and Market Overview
  6.3.2 Historic and Forecasted Market Size in Value USD and Volume Units (2017-2032F)
  6.3.3 Key Market Trends, Growth Factors and Opportunities
  6.3.4 Research and development: Geographic Segmentation Analysis
 6.4 Process development
  6.4.1 Introduction and Market Overview
  6.4.2 Historic and Forecasted Market Size in Value USD and Volume Units (2017-2032F)
  6.4.3 Key Market Trends, Growth Factors and Opportunities
  6.4.4 Process development: Geographic Segmentation Analysis
 6.5 Bioproduction
  6.5.1 Introduction and Market Overview
  6.5.2 Historic and Forecasted Market Size in Value USD and Volume Units (2017-2032F)
  6.5.3 Key Market Trends, Growth Factors and Opportunities
  6.5.4 Bioproduction: Geographic Segmentation Analysis

Chapter 7: Single-Use Bioreactor Market by End-User
 7.1 Single-Use Bioreactor Market Snapshot and Growth Engine
 7.2 Single-Use Bioreactor Market Overview
 7.3 Biopharmaceutical manufacturers
  7.3.1 Introduction and Market Overview
  7.3.2 Historic and Forecasted Market Size in Value USD and Volume Units (2017-2032F)
  7.3.3 Key Market Trends, Growth Factors and Opportunities
  7.3.4 Biopharmaceutical manufacturers: Geographic Segmentation Analysis
 7.4 Contract research organizations
  7.4.1 Introduction and Market Overview
  7.4.2 Historic and Forecasted Market Size in Value USD and Volume Units (2017-2032F)
  7.4.3 Key Market Trends, Growth Factors and Opportunities
  7.4.4 Contract research organizations: Geographic Segmentation Analysis
 7.5 Contract manufacturing organizations
  7.5.1 Introduction and Market Overview
  7.5.2 Historic and Forecasted Market Size in Value USD and Volume Units (2017-2032F)
  7.5.3 Key Market Trends, Growth Factors and Opportunities
  7.5.4 Contract manufacturing organizations: Geographic Segmentation Analysis
 7.6 Academic and research institutes
  7.6.1 Introduction and Market Overview
  7.6.2 Historic and Forecasted Market Size in Value USD and Volume Units (2017-2032F)
  7.6.3 Key Market Trends, Growth Factors and Opportunities
  7.6.4 Academic and research institutes: Geographic Segmentation Analysis

Chapter 8: Company Profiles and Competitive Analysis
 8.1 Competitive Landscape
  8.1.1 Competitive Benchmarking
  8.1.2 Single-Use Bioreactor Market Share by Manufacturer (2023)
  8.1.3 Industry BCG Matrix
  8.1.4 Heat Map Analysis
  8.1.5 Mergers and Acquisitions
  
 8.2 THERMO FISHER SCIENTIFIC (UNITED STATES)
  8.2.1 Company Overview
  8.2.2 Key Executives
  8.2.3 Company Snapshot
  8.2.4 Role of the Company in the Market
  8.2.5 Sustainability and Social Responsibility
  8.2.6 Operating Business Segments
  8.2.7 Product Portfolio
  8.2.8 Business Performance
  8.2.9 Key Strategic Moves and Recent Developments
  8.2.10 SWOT Analysis
 8.3 SARTORIUS AG (GERMANY)
 8.4 DANAHER CORPORATION (UNITED STATES)
 8.5 MERCK KGAA (GERMANY)
 8.6 GE HEALTHCARE (UNITED STATES)
 8.7 EPPENDORF AG (GERMANY)
 8.8 CESCO BIOENGINEERING CO
 8.9 LTD (TAIWAN)
 8.10 PBS BIOTECH
 8.11 INC (UNITED STATES)
 8.12 DISTEK
 8.13 INC(UNITED STATES)
 8.14 AND SOLIDA BIOTECH GMBH (GERMANY)
 8.15 OTHER ACTIVE PLAYERS

Chapter 9: Global Single-Use Bioreactor Market By Region
 9.1 Overview
 9.2. North America Single-Use Bioreactor Market
  9.2.1 Key Market Trends, Growth Factors and Opportunities
  9.2.2 Top Key Companies
  9.2.3 Historic and Forecasted Market Size by Segments
  9.2.4 Historic and Forecasted Market Size By Product Type
  9.2.4.1 Single-use bioreactor systems
  9.2.4.2 Media bags
  9.2.4.3 Filtration assemblies
  9.2.5 Historic and Forecasted Market Size By Cell Type
  9.2.5.1 Mammalian cells
  9.2.5.2 Bacterial cells
  9.2.5.3 Yeast cells
  9.2.5.4
  9.2.6 Historic and Forecasted Market Size By Application
  9.2.6.1 Research and development
  9.2.6.2 Process development
  9.2.6.3 Bioproduction
  9.2.7 Historic and Forecasted Market Size By End-User
  9.2.7.1 Biopharmaceutical manufacturers
  9.2.7.2 Contract research organizations
  9.2.7.3 Contract manufacturing organizations
  9.2.7.4 Academic and research institutes
  9.2.8 Historic and Forecast Market Size by Country
  9.2.8.1 US
  9.2.8.2 Canada
  9.2.8.3 Mexico
 9.3. Eastern Europe Single-Use Bioreactor Market
  9.3.1 Key Market Trends, Growth Factors and Opportunities
  9.3.2 Top Key Companies
  9.3.3 Historic and Forecasted Market Size by Segments
  9.3.4 Historic and Forecasted Market Size By Product Type
  9.3.4.1 Single-use bioreactor systems
  9.3.4.2 Media bags
  9.3.4.3 Filtration assemblies
  9.3.5 Historic and Forecasted Market Size By Cell Type
  9.3.5.1 Mammalian cells
  9.3.5.2 Bacterial cells
  9.3.5.3 Yeast cells
  9.3.5.4
  9.3.6 Historic and Forecasted Market Size By Application
  9.3.6.1 Research and development
  9.3.6.2 Process development
  9.3.6.3 Bioproduction
  9.3.7 Historic and Forecasted Market Size By End-User
  9.3.7.1 Biopharmaceutical manufacturers
  9.3.7.2 Contract research organizations
  9.3.7.3 Contract manufacturing organizations
  9.3.7.4 Academic and research institutes
  9.3.8 Historic and Forecast Market Size by Country
  9.3.8.1 Bulgaria
  9.3.8.2 The Czech Republic
  9.3.8.3 Hungary
  9.3.8.4 Poland
  9.3.8.5 Romania
  9.3.8.6 Rest of Eastern Europe
 9.4. Western Europe Single-Use Bioreactor Market
  9.4.1 Key Market Trends, Growth Factors and Opportunities
  9.4.2 Top Key Companies
  9.4.3 Historic and Forecasted Market Size by Segments
  9.4.4 Historic and Forecasted Market Size By Product Type
  9.4.4.1 Single-use bioreactor systems
  9.4.4.2 Media bags
  9.4.4.3 Filtration assemblies
  9.4.5 Historic and Forecasted Market Size By Cell Type
  9.4.5.1 Mammalian cells
  9.4.5.2 Bacterial cells
  9.4.5.3 Yeast cells
  9.4.5.4
  9.4.6 Historic and Forecasted Market Size By Application
  9.4.6.1 Research and development
  9.4.6.2 Process development
  9.4.6.3 Bioproduction
  9.4.7 Historic and Forecasted Market Size By End-User
  9.4.7.1 Biopharmaceutical manufacturers
  9.4.7.2 Contract research organizations
  9.4.7.3 Contract manufacturing organizations
  9.4.7.4 Academic and research institutes
  9.4.8 Historic and Forecast Market Size by Country
  9.4.8.1 Germany
  9.4.8.2 UK
  9.4.8.3 France
  9.4.8.4 Netherlands
  9.4.8.5 Italy
  9.4.8.6 Russia
  9.4.8.7 Spain
  9.4.8.8 Rest of Western Europe
 9.5. Asia Pacific Single-Use Bioreactor Market
  9.5.1 Key Market Trends, Growth Factors and Opportunities
  9.5.2 Top Key Companies
  9.5.3 Historic and Forecasted Market Size by Segments
  9.5.4 Historic and Forecasted Market Size By Product Type
  9.5.4.1 Single-use bioreactor systems
  9.5.4.2 Media bags
  9.5.4.3 Filtration assemblies
  9.5.5 Historic and Forecasted Market Size By Cell Type
  9.5.5.1 Mammalian cells
  9.5.5.2 Bacterial cells
  9.5.5.3 Yeast cells
  9.5.5.4
  9.5.6 Historic and Forecasted Market Size By Application
  9.5.6.1 Research and development
  9.5.6.2 Process development
  9.5.6.3 Bioproduction
  9.5.7 Historic and Forecasted Market Size By End-User
  9.5.7.1 Biopharmaceutical manufacturers
  9.5.7.2 Contract research organizations
  9.5.7.3 Contract manufacturing organizations
  9.5.7.4 Academic and research institutes
  9.5.8 Historic and Forecast Market Size by Country
  9.5.8.1 China
  9.5.8.2 India
  9.5.8.3 Japan
  9.5.8.4 South Korea
  9.5.8.5 Malaysia
  9.5.8.6 Thailand
  9.5.8.7 Vietnam
  9.5.8.8 The Philippines
  9.5.8.9 Australia
  9.5.8.10 New Zealand
  9.5.8.11 Rest of APAC
 9.6. Middle East & Africa Single-Use Bioreactor Market
  9.6.1 Key Market Trends, Growth Factors and Opportunities
  9.6.2 Top Key Companies
  9.6.3 Historic and Forecasted Market Size by Segments
  9.6.4 Historic and Forecasted Market Size By Product Type
  9.6.4.1 Single-use bioreactor systems
  9.6.4.2 Media bags
  9.6.4.3 Filtration assemblies
  9.6.5 Historic and Forecasted Market Size By Cell Type
  9.6.5.1 Mammalian cells
  9.6.5.2 Bacterial cells
  9.6.5.3 Yeast cells
  9.6.5.4
  9.6.6 Historic and Forecasted Market Size By Application
  9.6.6.1 Research and development
  9.6.6.2 Process development
  9.6.6.3 Bioproduction
  9.6.7 Historic and Forecasted Market Size By End-User
  9.6.7.1 Biopharmaceutical manufacturers
  9.6.7.2 Contract research organizations
  9.6.7.3 Contract manufacturing organizations
  9.6.7.4 Academic and research institutes
  9.6.8 Historic and Forecast Market Size by Country
  9.6.8.1 Turkey
  9.6.8.2 Bahrain
  9.6.8.3 Kuwait
  9.6.8.4 Saudi Arabia
  9.6.8.5 Qatar
  9.6.8.6 UAE
  9.6.8.7 Israel
  9.6.8.8 South Africa
 9.7. South America Single-Use Bioreactor Market
  9.7.1 Key Market Trends, Growth Factors and Opportunities
  9.7.2 Top Key Companies
  9.7.3 Historic and Forecasted Market Size by Segments
  9.7.4 Historic and Forecasted Market Size By Product Type
  9.7.4.1 Single-use bioreactor systems
  9.7.4.2 Media bags
  9.7.4.3 Filtration assemblies
  9.7.5 Historic and Forecasted Market Size By Cell Type
  9.7.5.1 Mammalian cells
  9.7.5.2 Bacterial cells
  9.7.5.3 Yeast cells
  9.7.5.4
  9.7.6 Historic and Forecasted Market Size By Application
  9.7.6.1 Research and development
  9.7.6.2 Process development
  9.7.6.3 Bioproduction
  9.7.7 Historic and Forecasted Market Size By End-User
  9.7.7.1 Biopharmaceutical manufacturers
  9.7.7.2 Contract research organizations
  9.7.7.3 Contract manufacturing organizations
  9.7.7.4 Academic and research institutes
  9.7.8 Historic and Forecast Market Size by Country
  9.7.8.1 Brazil
  9.7.8.2 Argentina
  9.7.8.3 Rest of SA

Chapter 10 Analyst Viewpoint and Conclusion
10.1 Recommendations and Concluding Analysis
10.2 Potential Market Strategies

Chapter 11 Research Methodology
11.1 Research Process
11.2 Primary Research
11.3 Secondary Research