Whole Exome Sequencing Market - Comprehensive Study Report & Recent Trends

Whole Exome Sequencing Market Synopsis:

Whole Exome Sequencing Market Size Was Valued at USD 2.33 Billion in 2023, and is Projected to Reach USD 10.29 Billion by 2032, Growing at a CAGR of 17.94% From 2024-2032.

Next generation sequencing (NGS) method, Whole Exome Sequencing (WES) targets the exomes of the individual that encompass virtually all of the genes in the human genome. These regions, which account for 1–2% of the genome size, accommodate a majority of documented pathogenic genetic alterations. WES can be used to identify genetic variations linked to diseases including rare diseases, cancers and other diseases and is cheaper and faster than WGS.

Whole Exome Sequencing has revolutionalized the field of genetics and clinical diagnosis by allowing for the correct analysis of mutations within amino acid coding genes. The technology has numerous methods of application including associated with the diagnosis of rare diseases, cancer, and pharmacogenomics. Compared to whole-genome sequencing, WES is more economical but offers the identification of important genomic sites that drive phenotype and disease outcomes.

In clinical diagnostic, WES is used to identify genetic disorders and is usually used where other methods may not work. Scientists use WES health interventions since it can help discover new genes that underlie diseases and hence assist in finding other treatments. The utilization of the enhanced bioinformatics and data analysis keeps the advancement in recognizing the result from the exome sequencing better and strong, which facilitate in the development of personalized medicine. Nevertheless there are several issues which can be regarded as disadvantageous for the market these are high costs in molecular diagnostic, sometimes confusing results interpretation and ethical issues on genetic testing.

Whole Exome Sequencing Market Trend Analysis:

Increasing Adoption of Cloud-Based Data Analysis Platforms

• Whole exome sequencing is creating an avalanche of data and, therefore, efficient and effective solutions for storing, analyzing, and sharing are needed now. What has come out as a trend in this market is the deployment of cloud based platforms where researchers as well as clinicians can enhance the ability to process sequencing data. These platforms are scalable, secure and provide advanced computational support which are crucicil to modern day WES workflows.
• For instance, cloud solutions use machine learning thes AI to increase the speed of variant interpreting and the reliability of diagnoses. There is a tendency for companies to partner with cloud service providers as this is becoming a popular way of providing solutions to a rising need of safety and efficiency in handling data within genomics and healthcare industries. This trend is expected to continue indirectly, promoting greater innovation and better access to WES services internationally.

Expanding Role of WES in Personalized Medicine

• The use of personalized medicine is a massive opportunity for the expansion of the WES market. As a result, WES can offer the most effective and personalized treatment due to the identification of certain gene changes. More specifically, this approach is highly useful in oncology as WES helps decide the mutations unique to the tumor and applies the targeted therapies.
• However, availability of novel bioinformatics tools and decreasing cost of sequencing is increasing the utility of WES in the clinical leading arena. The heightened focus on precision medicine programs by governments and WHO promotes the use of WES and provides great opportunities for development in both developed and emerging countries.

Whole Exome Sequencing Market Segment Analysis:

Whole Exome Sequencing Market is Segmented on the basis of Product & Service, Technology, Application, End user, and Region

By Product & Service, Systems segment is expected to dominate the market during the forecast period

• The market for Whole Exome Sequencing can be divided into systems, kits and services. Systems refer to the sequencing hardware and can be expensive especially during purchase because of the initial investments. Library preparation and sequencing kits, among other kits, are formidable growth drivers given their status as consumables that generate regular orders. Other areas as sequencing, data analysis and data interpretation have emerged as services because people require integrated solutions.
• The services segment is projected to grow at a faster rate due to rising outsourcing of the research and diagnostics services. This growth is accompanied by full end-to-end service providers, thereby eliminating many bottlenecks in processes such as sample preparation and data analysis and interpretation which was otherwise to be done by the research facilities and clinical laboratories.

By Application, Diagnostics segment expected to held the largest share

• Whole Exome Sequencing is useful in diagnostics, and drug discovery and development, pharmacogenomics, and pharmacogenetics. Diagnostics accounts for the largest share as more and more people are getting their genomes sequenced through WES to relate diseases to particular genetic changes and cancer, for instance.
• Targeted or personalized medicine is an exciting niche that requires differentiation due to scientific developments in genomics and movement towards such products. drug discovery and development also use WES to look for candidate drug targets accelerates the process of introducing new medications to the population. This versatility alone speaks volumes for the sustainability of this particular market technology.

Whole Exome Sequencing Market Regional Insights:

North America is Expected to Dominate the Market Over the Forecast period

• Currently the Whole Exome Sequencing market is headed by North America due to well-equipped healthcare systems, huge investment in genomics and steadily increasing trends for precision medicine. The participation of leading market players and government approbation of genomic research enhance the region’s leadership, too.
• Furthermore, beneficial reimbursement policies of the genetic testing and adoption of WES as a clinical practice added fuel to the fire. The strong base of R&D in the region along with the increasing realization of the growth possibilities of WES, thus putting it in the spotlight of the world market.

Active Key Players in the Whole Exome Sequencing Market:

• Illumina, Inc. (United States)
• Thermo Fisher Scientific Inc. (United States)
• Agilent Technologies, Inc. (United States)
• Roche Diagnostics (Switzerland)
• BGI Genomics (China)
• PerkinElmer, Inc. (United States)
• Pacific Biosciences of California, Inc. (United States)
• GENEWIZ (United States)
• Macrogen, Inc. (South Korea)
• Eurofins Scientific (Luxembourg)
• F. Hoffmann-La Roche Ltd. (Switzerland)
• Oxford Nanopore Technologies Ltd. (United Kingdom)
• Other Active Players

Key Industry Developments in the Whole Exome Sequencing Market:

• In March 2023 Illumina Inc., launched its newly developed NovaSeq 6000 v3 sequencing system. This system offers enhanced sequence precision, accuracy, higher scalability, and top speed, which will strengthen Illumina's leadership in the market.
• In January 2023, QIAGEN Digital Insights (QDI), the bioinformatics division of QIAGEN, has unveiled an upgraded version of the QIAGEN CLC Genomics Workbench Premium, designed to eliminate the data-analysis bottleneck in next-generation sequencing (NGS). The enhanced platform significantly boosts analysis speed, enabling faster and more efficient interpretation of whole genome sequencing (WGS), whole exome sequencing (WES), and large panel sequencing data.

Chapter 1: Introduction
 1.1 Scope and Coverage

Chapter 2:Executive Summary

Chapter 3: Market Landscape
 3.1 Market Dynamics
  3.1.1 Drivers
  3.1.2 Restraints
  3.1.3 Opportunities
  3.1.4 Challenges
 3.2 Market Trend Analysis
 3.3 PESTLE Analysis
 3.4 Porter's Five Forces Analysis
 3.5 Industry Value Chain Analysis
 3.6 Ecosystem
 3.7 Regulatory Landscape
 3.8 Price Trend Analysis
 3.9 Patent Analysis
 3.10 Technology Evolution
 3.11 Investment Pockets
 3.12 Import-Export Analysis

Chapter 4: Whole Exome Sequencing Market by Product & Service
 4.1 Whole Exome Sequencing Market Snapshot and Growth Engine
 4.2 Whole Exome Sequencing Market Overview
 4.3 Systems
  4.3.1 Introduction and Market Overview
  4.3.2 Historic and Forecasted Market Size in Value USD and Volume Units (2017-2032F)
  4.3.3 Key Market Trends, Growth Factors and Opportunities
  4.3.4 Systems: Geographic Segmentation Analysis
 4.4 Kits
  4.4.1 Introduction and Market Overview
  4.4.2 Historic and Forecasted Market Size in Value USD and Volume Units (2017-2032F)
  4.4.3 Key Market Trends, Growth Factors and Opportunities
  4.4.4 Kits: Geographic Segmentation Analysis
 4.5 Services
  4.5.1 Introduction and Market Overview
  4.5.2 Historic and Forecasted Market Size in Value USD and Volume Units (2017-2032F)
  4.5.3 Key Market Trends, Growth Factors and Opportunities
  4.5.4 Services: Geographic Segmentation Analysis

Chapter 5: Whole Exome Sequencing Market by Technology
 5.1 Whole Exome Sequencing Market Snapshot and Growth Engine
 5.2 Whole Exome Sequencing Market Overview
 5.3 Sequencing Synthesis
  5.3.1 Introduction and Market Overview
  5.3.2 Historic and Forecasted Market Size in Value USD and Volume Units (2017-2032F)
  5.3.3 Key Market Trends, Growth Factors and Opportunities
  5.3.4 Sequencing Synthesis: Geographic Segmentation Analysis
 5.4 Ion Semiconductor Sequencing
  5.4.1 Introduction and Market Overview
  5.4.2 Historic and Forecasted Market Size in Value USD and Volume Units (2017-2032F)
  5.4.3 Key Market Trends, Growth Factors and Opportunities
  5.4.4 Ion Semiconductor Sequencing: Geographic Segmentation Analysis
 5.5 Other
  5.5.1 Introduction and Market Overview
  5.5.2 Historic and Forecasted Market Size in Value USD and Volume Units (2017-2032F)
  5.5.3 Key Market Trends, Growth Factors and Opportunities
  5.5.4 Other: Geographic Segmentation Analysis

Chapter 6: Whole Exome Sequencing Market by Application
 6.1 Whole Exome Sequencing Market Snapshot and Growth Engine
 6.2 Whole Exome Sequencing Market Overview
 6.3 Diagnostics
  6.3.1 Introduction and Market Overview
  6.3.2 Historic and Forecasted Market Size in Value USD and Volume Units (2017-2032F)
  6.3.3 Key Market Trends, Growth Factors and Opportunities
  6.3.4 Diagnostics: Geographic Segmentation Analysis
 6.4 Drug Discovery and Development
  6.4.1 Introduction and Market Overview
  6.4.2 Historic and Forecasted Market Size in Value USD and Volume Units (2017-2032F)
  6.4.3 Key Market Trends, Growth Factors and Opportunities
  6.4.4 Drug Discovery and Development: Geographic Segmentation Analysis
 6.5 Personalized Medicine
  6.5.1 Introduction and Market Overview
  6.5.2 Historic and Forecasted Market Size in Value USD and Volume Units (2017-2032F)
  6.5.3 Key Market Trends, Growth Factors and Opportunities
  6.5.4 Personalized Medicine: Geographic Segmentation Analysis
 6.6 Other
  6.6.1 Introduction and Market Overview
  6.6.2 Historic and Forecasted Market Size in Value USD and Volume Units (2017-2032F)
  6.6.3 Key Market Trends, Growth Factors and Opportunities
  6.6.4 Other: Geographic Segmentation Analysis

Chapter 7: Whole Exome Sequencing Market by End User
 7.1 Whole Exome Sequencing Market Snapshot and Growth Engine
 7.2 Whole Exome Sequencing Market Overview
 7.3 Research Centers and Academic Institutions
  7.3.1 Introduction and Market Overview
  7.3.2 Historic and Forecasted Market Size in Value USD and Volume Units (2017-2032F)
  7.3.3 Key Market Trends, Growth Factors and Opportunities
  7.3.4 Research Centers and Academic Institutions: Geographic Segmentation Analysis
 7.4 Hospitals and Clinics
  7.4.1 Introduction and Market Overview
  7.4.2 Historic and Forecasted Market Size in Value USD and Volume Units (2017-2032F)
  7.4.3 Key Market Trends, Growth Factors and Opportunities
  7.4.4 Hospitals and Clinics: Geographic Segmentation Analysis
 7.5 Pharmaceutical and Biotechnology Companies
  7.5.1 Introduction and Market Overview
  7.5.2 Historic and Forecasted Market Size in Value USD and Volume Units (2017-2032F)
  7.5.3 Key Market Trends, Growth Factors and Opportunities
  7.5.4 Pharmaceutical and Biotechnology Companies: Geographic Segmentation Analysis
 7.6 Other
  7.6.1 Introduction and Market Overview
  7.6.2 Historic and Forecasted Market Size in Value USD and Volume Units (2017-2032F)
  7.6.3 Key Market Trends, Growth Factors and Opportunities
  7.6.4 Other: Geographic Segmentation Analysis

Chapter 8: Company Profiles and Competitive Analysis
 8.1 Competitive Landscape
  8.1.1 Competitive Benchmarking
  8.1.2 Whole Exome Sequencing Market Share by Manufacturer (2023)
  8.1.3 Industry BCG Matrix
  8.1.4 Heat Map Analysis
  8.1.5 Mergers and Acquisitions  
 8.2 ILLUMINA INC. (UNITED STATES)
  8.2.1 Company Overview
  8.2.2 Key Executives
  8.2.3 Company Snapshot
  8.2.4 Role of the Company in the Market
  8.2.5 Sustainability and Social Responsibility
  8.2.6 Operating Business Segments
  8.2.7 Product Portfolio
  8.2.8 Business Performance
  8.2.9 Key Strategic Moves and Recent Developments
  8.2.10 SWOT Analysis
 8.3 THERMO FISHER SCIENTIFIC INC. (UNITED STATES)
 8.4 AGILENT TECHNOLOGIES INC. (UNITED STATES)
 8.5 ROCHE DIAGNOSTICS (SWITZERLAND)
 8.6 BGI GENOMICS (CHINA)
 8.7 PERKINELMER INC. (UNITED STATES)
 8.8 PACIFIC
 8.9 BIOSCIENCES OF CALIFORNIA INC. (UNITED STATES)
 8.10 GENEWIZ (UNITED STATES)
 8.11 MACROGEN INC. (SOUTH KOREA)
 8.12 EUROFINS SCIENTIFIC (LUXEMBOURG)
 8.13 F. HOFFMANN-LA ROCHE LTD. (SWITZERLAND)
 8.14 OXFORD NANOPORE TECHNOLOGIES LTD. (UNITED KINGDOM)
 8.15 OTHER ACTIVE PLAYERS

Chapter 9: Global Whole Exome Sequencing Market By Region
 9.1 Overview
 9.2. North America Whole Exome Sequencing Market
  9.2.1 Key Market Trends, Growth Factors and Opportunities
  9.2.2 Top Key Companies
  9.2.3 Historic and Forecasted Market Size by Segments
  9.2.4 Historic and Forecasted Market Size By Product & Service
  9.2.4.1 Systems
  9.2.4.2 Kits
  9.2.4.3 Services
  9.2.5 Historic and Forecasted Market Size By Technology
  9.2.5.1 Sequencing Synthesis
  9.2.5.2 Ion Semiconductor Sequencing
  9.2.5.3 Other
  9.2.6 Historic and Forecasted Market Size By Application
  9.2.6.1 Diagnostics
  9.2.6.2 Drug Discovery and Development
  9.2.6.3 Personalized Medicine
  9.2.6.4 Other
  9.2.7 Historic and Forecasted Market Size By End User
  9.2.7.1 Research Centers and Academic Institutions
  9.2.7.2 Hospitals and Clinics
  9.2.7.3 Pharmaceutical and Biotechnology Companies
  9.2.7.4 Other
  9.2.8 Historic and Forecast Market Size by Country
  9.2.8.1 US
  9.2.8.2 Canada
  9.2.8.3 Mexico
 9.3. Eastern Europe Whole Exome Sequencing Market
  9.3.1 Key Market Trends, Growth Factors and Opportunities
  9.3.2 Top Key Companies
  9.3.3 Historic and Forecasted Market Size by Segments
  9.3.4 Historic and Forecasted Market Size By Product & Service
  9.3.4.1 Systems
  9.3.4.2 Kits
  9.3.4.3 Services
  9.3.5 Historic and Forecasted Market Size By Technology
  9.3.5.1 Sequencing Synthesis
  9.3.5.2 Ion Semiconductor Sequencing
  9.3.5.3 Other
  9.3.6 Historic and Forecasted Market Size By Application
  9.3.6.1 Diagnostics
  9.3.6.2 Drug Discovery and Development
  9.3.6.3 Personalized Medicine
  9.3.6.4 Other
  9.3.7 Historic and Forecasted Market Size By End User
  9.3.7.1 Research Centers and Academic Institutions
  9.3.7.2 Hospitals and Clinics
  9.3.7.3 Pharmaceutical and Biotechnology Companies
  9.3.7.4 Other
  9.3.8 Historic and Forecast Market Size by Country
  9.3.8.1 Russia
  9.3.8.2 Bulgaria
  9.3.8.3 The Czech Republic
  9.3.8.4 Hungary
  9.3.8.5 Poland
  9.3.8.6 Romania
  9.3.8.7 Rest of Eastern Europe
 9.4. Western Europe Whole Exome Sequencing Market
  9.4.1 Key Market Trends, Growth Factors and Opportunities
  9.4.2 Top Key Companies
  9.4.3 Historic and Forecasted Market Size by Segments
  9.4.4 Historic and Forecasted Market Size By Product & Service
  9.4.4.1 Systems
  9.4.4.2 Kits
  9.4.4.3 Services
  9.4.5 Historic and Forecasted Market Size By Technology
  9.4.5.1 Sequencing Synthesis
  9.4.5.2 Ion Semiconductor Sequencing
  9.4.5.3 Other
  9.4.6 Historic and Forecasted Market Size By Application
  9.4.6.1 Diagnostics
  9.4.6.2 Drug Discovery and Development
  9.4.6.3 Personalized Medicine
  9.4.6.4 Other
  9.4.7 Historic and Forecasted Market Size By End User
  9.4.7.1 Research Centers and Academic Institutions
  9.4.7.2 Hospitals and Clinics
  9.4.7.3 Pharmaceutical and Biotechnology Companies
  9.4.7.4 Other
  9.4.8 Historic and Forecast Market Size by Country
  9.4.8.1 Germany
  9.4.8.2 UK
  9.4.8.3 France
  9.4.8.4 The Netherlands
  9.4.8.5 Italy
  9.4.8.6 Spain
  9.4.8.7 Rest of Western Europe
 9.5. Asia Pacific Whole Exome Sequencing Market
  9.5.1 Key Market Trends, Growth Factors and Opportunities
  9.5.2 Top Key Companies
  9.5.3 Historic and Forecasted Market Size by Segments
  9.5.4 Historic and Forecasted Market Size By Product & Service
  9.5.4.1 Systems
  9.5.4.2 Kits
  9.5.4.3 Services
  9.5.5 Historic and Forecasted Market Size By Technology
  9.5.5.1 Sequencing Synthesis
  9.5.5.2 Ion Semiconductor Sequencing
  9.5.5.3 Other
  9.5.6 Historic and Forecasted Market Size By Application
  9.5.6.1 Diagnostics
  9.5.6.2 Drug Discovery and Development
  9.5.6.3 Personalized Medicine
  9.5.6.4 Other
  9.5.7 Historic and Forecasted Market Size By End User
  9.5.7.1 Research Centers and Academic Institutions
  9.5.7.2 Hospitals and Clinics
  9.5.7.3 Pharmaceutical and Biotechnology Companies
  9.5.7.4 Other
  9.5.8 Historic and Forecast Market Size by Country
  9.5.8.1 China
  9.5.8.2 India
  9.5.8.3 Japan
  9.5.8.4 South Korea
  9.5.8.5 Malaysia
  9.5.8.6 Thailand
  9.5.8.7 Vietnam
  9.5.8.8 The Philippines
  9.5.8.9 Australia
  9.5.8.10 New Zealand
  9.5.8.11 Rest of APAC
 9.6. Middle East & Africa Whole Exome Sequencing Market
  9.6.1 Key Market Trends, Growth Factors and Opportunities
  9.6.2 Top Key Companies
  9.6.3 Historic and Forecasted Market Size by Segments
  9.6.4 Historic and Forecasted Market Size By Product & Service
  9.6.4.1 Systems
  9.6.4.2 Kits
  9.6.4.3 Services
  9.6.5 Historic and Forecasted Market Size By Technology
  9.6.5.1 Sequencing Synthesis
  9.6.5.2 Ion Semiconductor Sequencing
  9.6.5.3 Other
  9.6.6 Historic and Forecasted Market Size By Application
  9.6.6.1 Diagnostics
  9.6.6.2 Drug Discovery and Development
  9.6.6.3 Personalized Medicine
  9.6.6.4 Other
  9.6.7 Historic and Forecasted Market Size By End User
  9.6.7.1 Research Centers and Academic Institutions
  9.6.7.2 Hospitals and Clinics
  9.6.7.3 Pharmaceutical and Biotechnology Companies
  9.6.7.4 Other
  9.6.8 Historic and Forecast Market Size by Country
  9.6.8.1 Turkiye
  9.6.8.2 Bahrain
  9.6.8.3 Kuwait
  9.6.8.4 Saudi Arabia
  9.6.8.5 Qatar
  9.6.8.6 UAE
  9.6.8.7 Israel
  9.6.8.8 South Africa
 9.7. South America Whole Exome Sequencing Market
  9.7.1 Key Market Trends, Growth Factors and Opportunities
  9.7.2 Top Key Companies
  9.7.3 Historic and Forecasted Market Size by Segments
  9.7.4 Historic and Forecasted Market Size By Product & Service
  9.7.4.1 Systems
  9.7.4.2 Kits
  9.7.4.3 Services
  9.7.5 Historic and Forecasted Market Size By Technology
  9.7.5.1 Sequencing Synthesis
  9.7.5.2 Ion Semiconductor Sequencing
  9.7.5.3 Other
  9.7.6 Historic and Forecasted Market Size By Application
  9.7.6.1 Diagnostics
  9.7.6.2 Drug Discovery and Development
  9.7.6.3 Personalized Medicine
  9.7.6.4 Other
  9.7.7 Historic and Forecasted Market Size By End User
  9.7.7.1 Research Centers and Academic Institutions
  9.7.7.2 Hospitals and Clinics
  9.7.7.3 Pharmaceutical and Biotechnology Companies
  9.7.7.4 Other
  9.7.8 Historic and Forecast Market Size by Country
  9.7.8.1 Brazil
  9.7.8.2 Argentina
  9.7.8.3 Rest of SA

Chapter 10 Analyst Viewpoint and Conclusion
10.1 Recommendations and Concluding Analysis
10.2 Potential Market Strategies

Chapter 11 Research Methodology
11.1 Research Process
11.2 Primary Research
11.3 Secondary Research